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Which pain block wins for gallbladder surgery?

NCT ID NCT07377877

Symptom relief Sponsor: Karabuk University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two ultrasound-guided nerve blocks—external oblique intercostal block and erector spinae plane block—for pain after laparoscopic gallbladder removal. Sixty adults received one of the blocks before surgery, and researchers measured their opioid use and pain scores for 24 hours. The goal is to find which block provides better pain relief and faster recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If one block works better, it could become the standard choice for pain control after gallbladder surgery, reducing opioid use and speeding recovery.
What could go wrong
This is a small, completed study with only 60 participants. Results may not apply to all patients or surgeries, and both blocks carry rare risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Jan 2026

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Age between 18 and 80 years * Scheduled to undergo elective laparoscopic cholecystectomy * Classified as American Society of Anesthesiologists (ASA) physical status I-III * Ability to understand and operate a patient-controlled analgesia (PCA) device * Provision of written informed consent Exclusion Criteria * History of chronic opioid use for more than four weeks prior to surgery * Presence of pre-existing chronic pain conditions, such as migraine or fibromyalgia * History of alcohol or substance abuse * Known hypersensitivity or allergy to local anesthetics or opioids * Presence of severe organ dysfunction, including clinically significant hepatic or renal disease * Any contraindication to regional anesthesia * Severe psychiatric disorders impairing patient cooperation or the ability to reliably assess pain (e.g., psychosis, dementia) * Pregnancy or breastfeeding * Presence of hematological disorders

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Erector spina plan block External oblique intercostal block Pain management

Contacts and locations

Locations

  • Department of Anesthesiology and Reanimation, Samsun City Hospital

    Samsun, 55200, Turkey (Türkiye)

  • Karabuk Training and Research Hospital, Department of Anesthesiology and Reanimation

    Karabük, 78200, Turkey (Türkiye)

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