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New numbing technique may make wisdom tooth extraction less painful and scary

NCT ID NCT06852066

Symptom relief Sponsor: Afyonkarahisar Health Sciences University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two ways of giving numbing medicine for impacted wisdom tooth surgery in 40 healthy adults aged 18-40. One method used a computer-assisted device, the other was the standard injection. Researchers measured pain, anxiety, and vital signs like blood pressure and heart rate during the procedure to see which technique offered a better experience.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Mar 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Participants must meet all of the following criteria to be included in the study: * Must be between 18 and 40 years old * Must have bilaterally impacted mandibular third molars with bone retention * Impacted teeth must be at a mesioangular angle, classified as Class 1-2 and A--B type (Pell \& Gregory classification) * Must have an impacted tooth difficulty level of 3-5 according to the Pederson Difficulty Index * Must be classified as ASA 1 (healthy individuals with no systemic diseases) * Must be able to read and understand questionnaire forms and provide informed consent Must voluntarily agree to participate in the study and sign the informed consent form Exclusion Criteria: Participants will be excluded from the study if they meet any of the following criteria: * Presence of any systemic disease (e.g., cardiovascular disease, liver disease, hematologic disorders, neoplastic diseases, rheumatic conditions, diabetes mellitus) * History of psychiatric disorders or current use of anxiolytics, antidepressants, or anticonvulsants * Use of anti-inflammatory, analgesic, or anxiolytic medications prior to the procedure that could affect pain, inflammation, or anxiety responses * Chronic medication use, including antihistamines, NSAIDs, steroids, or antidepressants * Presence of oral pathologies affecting pain perception (e.g., pulpitis, periodontitis, oral ulcers, cysts, or tumors) * Suspected or confirmed pregnancy or breastfeeding * Allergy to the local anesthetic (articaine) used in the study * Hearing impairment that could interfere with study participation * Presence of dentophobia (severe dental phobia)

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Comparison of the efficacy Computer assisted local anesthesia Hemodynamic changes Local anesthesia Molar, third Surgery, oral

Contacts and locations

Locations

  • Afyonkarahisar Health Sciences University, Faculty of Dentistry

    Afyonkarahisar, 03000, Turkey (Türkiye)

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