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New antibody drugs aim to block deadly clots in leg artery patients

NCT ID NCT07318610

First seen Jan 07, 2026 · Last updated May 21, 2026 · Updated 25 times

Summary

This study tests two experimental drugs, REGN7508 and REGN9933, to see if they can prevent life-threatening blood clots in people with peripheral artery disease (PAD) who recently had leg surgery to improve blood flow. About 7,050 adults will be randomly assigned to receive one of the study drugs, a standard blood thinner (rivaroxaban), or a placebo. The goal is to find a safer and more effective way to reduce clots like heart attacks, strokes, and limb loss.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Conditions

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