Could a slightly faster pacemaker setting boost brain blood flow?
NCT ID NCT07589452
First seen May 21, 2026 · Last updated Jun 21, 2026 · Updated 6 times
Summary
This study looks at whether setting a pacemaker to a personalized rate of 75 beats per minute (instead of the usual 50-60) can improve how well the heart fills with blood and how much blood reaches the brain. It includes 70 adults aged 65 and older who have high blood pressure and a slow heart rate, and who are getting a new pacemaker. Participants will be randomly assigned to either the personalized rate or the standard rate, and their heart and brain function will be checked after three months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pacemaker with personalized lower rate (75 bpm)
What this could lead to
If successful, this could show that a slightly faster pacemaker setting improves heart filling and blood flow to the brain in older adults with high blood pressure.
What could go wrong
This is a small, early-stage study with only 70 participants, so results may not apply to everyone. The intervention is a simple programming change, so risks are low but benefits may be modest.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.