Blood test for Alzheimer's marker could speed up memory care decisions
NCT ID NCT07140744
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a blood test for a protein called P-tau217 can help doctors make faster and better decisions for people with memory concerns. Researchers will compare what happens when doctors have the test results versus standard care. The study involves 7,000 participants and is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- P-tau217 blood biomarker test
- What this could lead to
- If successful, this blood test could help doctors detect Alzheimer's-related changes earlier and guide treatment decisions for people with memory complaints.
- What could go wrong
- This is a diagnostic study, not a treatment trial. The test may not change patient outcomes, and results could be uncertain or lead to unnecessary worry.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 7,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Health Care Provider (HCP) Definitions * Primary care physician (PCPs): physicians such as family medicine practitioners and internists who do not specialize in neurological care. * Secondary care physicians (SCPs): physicians such as geriatricians or neurologists who see patients for specific reasons. * Tertiary care physicians (TCPs): specialty neurologists who focus on certain neurological conditions. HCP Participant Selection Criteria * HCP inclusion criterion for each category of HCP is as follows: * Group 1: PCPs who routinely evaluate and manage patients over the age of 50 in a family practice or internist setting. * Group 2: SCPs and TCPs with experience diagnosing and treating patients with cognitive impairment and dementia. Additional inclusion criteria applying to HCPs in the interventional group: * Must be willing to review educational materials provided by the study sponsor, before enrolling patients. Patient Participant Criteria * Participants in the interventional group are eligible to be included in the study only if all the following criteria apply: * Are capable of giving, and have given, signed informed consent. * Have venous access sufficient to allow the protocol-required blood sampling. * Are reliable, willing, and able to make themselves available for the duration of the study and are willing to follow study procedures. Disease-specific Characteristics * Present to the HCP with 1 or more subjective cognitive impairment complaints (SCIC) in the 4 weeks prior to identification: for example, worsening of memory, misplacing items, difficulty concentrating, or new challenges with problem solving. Patient Participant Exclusion Criteria: * In the 18 months prior to identification have prior or associated HCP-ordered referral or prior prescription of drug therapies, for the SCIC * Participants with previous amyloid- or tau-specific tests, defined as * Amyloid position emission tomography (PET) * Tau PET * Cerebral spinal fluid (CSF) tests for amyloid beta (Aβ) and/or tau biomarkers, or * Blood tests for Aβ and/or tau biomarkers * Has a current serious or unstable illness that in the enrolling investigator's opinion could interfere with completion of the study or have a life expectancy of less than 1 year. * Has a known brain lesion, pathology, or prior alternative diagnosis that could explain the participant's clinical presentation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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SiteRx Virtual Site
RECRUITINGNew York, New York, 10013, United States
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