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Ozone boosts gum surgery results in periodontitis trial

NCT ID NCT07551297

Disease control Sponsor: Alparslan Dilsiz Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding ozone therapy to standard gum surgery improves outcomes for people with advanced gum disease (stage III periodontitis). Twenty-four adults received surgery on both sides of their mouth, with one side also getting ozone treatment. Researchers measured gum pocket depth and attachment levels over 12 months to see if ozone helped control the disease better than surgery alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Jan 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged between 25 and 65 years * Diagnosed with Stage III periodontitis * Presence of at least 20 teeth * Presence of periodontal pockets ≥5 mm in at least two teeth * Indication for open flap debridement * Systemically healthy individuals * No periodontal treatment within the last 6 months Exclusion Criteria: * Pregnant or breastfeeding women * Presence of systemic diseases that may affect periodontal healing * Use of antibiotics or anti-inflammatory drugs within the last 6 months * Smoking or tobacco use * History of periodontal treatment within the last 6 months * Patients with poor oral hygiene compliance

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontitis Stage III periodontitis

Contacts and locations

Locations

  • Ataturk University Faculty of Dentistry, Department of Periodontology

    Erzurum, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.