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Ozone therapy: a surprising muscle recovery boost?

NCT ID NCT07728422

Symptom relief Sponsor: Inonu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether different forms of ozone therapy can help healthy adults recover faster after muscle-damaging exercise. Participants will do a set of eccentric exercises, then receive either autohemotherapy (ozonated blood reinfused), ozone sauna, ozonated lavender oil massage, or no treatment. Blood samples are taken over 72 hours to measure markers of muscle damage and fatigue.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ozone therapy (autohemotherapy, ozone sauna, ozonated lavender oil massage)
What this could lead to
If effective, ozone therapy could offer a new way to speed up muscle recovery after intense exercise.
What could go wrong
This is a small, early-stage trial with only 32 participants, so results may not apply broadly. Ozone therapy also carries risks like infection or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Oct 2024

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * male football players aged 18-30 years * playing exclusively in the midfield position * active participation in regional professional football leagues (non-top-tier) * engagement in regular football training at least four sessions per week with a minimum duration of 90 minutes per session * absence of acute or chronic musculoskeletal injuries within the preceding six months * no use of anti-inflammatory medications or ergogenic supplements within the four weeks prior to the study Exclusion Criteria: * female football players * diagnosed cardiovascular, metabolic, or neurological disorders * known hypersensitivity to ozone exposure or lavender oil * any surgical intervention within the past six months * concurrent participation in alternative recovery or therapeutic interventions during the study period * playing positions other than midfield

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Muscle damage Oxidative stress Ozone therapy Recovery

Contacts and locations

Locations

  • Inonu University

    Malatya, Malatya, 44280, Turkey (Türkiye)

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