CoQ10 supplement tested for prostate relief

NCT ID NCT07638865

Symptom relief Sponsor: G.Gennimatas General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily CoQ10 supplement (Ralivia) can improve symptoms of benign prostatic hyperplasia (BPH), such as frequent or difficult urination. One hundred men aged 50–80 with moderate-to-severe BPH will receive either the supplement or a placebo for 3 months. Researchers will measure changes in symptom scores, urine flow, and prostate size to see if the supplement offers real relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: Coenzyme Q10 (CoQ10) supplement, called Ralivia
What this could lead to: If it works, this could offer a natural option to help men with enlarged prostate urinate more easily and with less discomfort.
What could go wrong: This is a small, early-stage trial with only 100 men. The supplement may work no better than a placebo, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 80 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Participant must be between 50 and 80 years old. 2. Participant has signed and dated the appropriate Informed Consent document. 3. International Prostate Symptom Score (IPSS) ≥8 and ≤30 4. Prostate volume ≥30gram and ≤80gram 5. Peak urinary flow rate (Qmax) ≥5 ml/sec and ≤15ml/sec 6. Post void residual volume ≤150ml Exclusion Criteria: 1. Current or recurrent urinary tract infection (UTI), prostatitis, gross hematuria (blood in urine without a known cause), or a history of urinary retention. 2. Participant has a history of prostate, bladder or urethral cancer. 3. Participant has undergone pelvic radiation or systemic chemotherapy. 4. Participant has undergone intravesical chemotherapy. 5. Participant has unilateral orchialgia without pelvic symptoms, active urethral stricture or bladder stones, or any other urological condition (except from BPH) associated with LUTS, any neurological disease or disorder affecting the bladder. 6. Participant has undergone prostate surgery 7. Participant with penile or urinary sphincter implants. 8. Diagnosed neurological conditions known to affect bladder function (e.g., multiple sclerosis, Parkinson's disease, or neurogenic bladder). 9. Significant medical conditions (e.g., unstable cardiac arrhythmias, uncontrolled diabetes, severe renal impairment) that pose an unreasonable risk to the patient or might interfere with study results. 10. Participant has been diagnosed with cancer during the last 5 years or had any surgery in the pelvis. 11. Participant has a neurological impairment or psychiatric disorder preventing his understanding of consent and his ability to comply with the protocol.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Benign prostate enlargement Benign prostate hypertrophy(BPH) Benign prostate obstruction (BPO)

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

CoQ10 supplement tested for prostate relief

What the study statuses mean