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New combo approach targets EGFR lung cancer with promising drug

NCT ID NCT06194448

First seen Nov 04, 2025 · Last updated May 21, 2026 · Updated 30 times

Summary

This study tests whether giving the targeted drug osimertinib before and after standard chemoradiation helps adults with a specific type of stage III lung cancer (EGFR mutation-positive) that cannot be removed by surgery. About 76 participants will receive osimertinib first, then chemoradiation, then continue osimertinib to keep the cancer under control. The goal is to see if this approach delays cancer growth and is safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    La Jolla, California, 92093, United States

  • Research Site

    Palo Alto, California, 94304, United States

  • Research Site

    Beijing, 100021, China

  • Research Site

    Changsha, 410013, China

  • Research Site

    Guangzhou, 510060, China

  • Research Site

    Hangzhou, 310022, China

  • Research Site

    Harbin, 150081, China

  • Research Site

    Hefei, 230001, China

  • Research Site

    Jinan, 250117, China

  • Research Site

    Nanning, 530021, China

  • Research Site

    Shanghai, 200032, China

  • Research Site

    Tianjin, 300060, China

  • Research Site

    Wuhan, 430022, China

  • Research Site

    Wuhan, 430071, China

  • Research Site

    Zhengzhou, 450052, China

  • Research Site

    Haifa, 31096, Israel

  • Research Site

    Jerusalem, 91031, Israel

  • Research Site

    Tel Aviv, 62748, Israel

  • Research Site

    Cheongju-si, 28644, South Korea

  • Research Site

    Seongnam-si, 13620, South Korea

  • Research Site

    Seoul, 03080, South Korea

  • Research Site

    Seoul, 03722, South Korea

  • Research Site

    Seoul, 06351, South Korea

  • Research Site

    Suwon, 16247, South Korea

  • Research Site

    Barcelona, 08003, Spain

  • Research Site

    Donostia / San Sebastian, 20014, Spain

  • Research Site

    Granada, 18016, Spain

  • Research Site

    Madrid, 28007, Spain

  • Research Site

    Tainan, 704, Taiwan

  • Research Site

    Taipei, 11217, Taiwan

  • Research Site

    Bangkok, 10210, Thailand

  • Research Site

    Bangkok, 10330, Thailand

  • Research Site

    Chiang Rai, 57000, Thailand

  • Research Site

    Hat Yai, 90110, Thailand

  • Research Site

    Khon Kaen, 40002, Thailand

  • Research Site

    Ankara, 06010, Turkey (Türkiye)

  • Research Site

    Yenimahalle, 06560, Turkey (Türkiye)

  • Research Site

    Hanoi, 100000, Vietnam

  • Research Site

    Ho Chi Minh City, 700000, Vietnam

Conditions

Explore the condition pages connected to this study.