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Could a Single-Dose antibiotic replace weeks of IV treatment for heart infections?

NCT ID NCT07550595

First seen May 04, 2026 · Last updated May 25, 2026 · Updated 6 times

Summary

This study tests a long-acting antibiotic called oritavancin for treating heart infections caused by certain bacteria. The goal is to see if this drug can work as well as standard treatments that require weeks of IV antibiotics in the hospital. Twenty adults with heart infections will receive oritavancin, with some getting standard doses and others doses adjusted based on drug levels in their blood. The study will check safety, effectiveness, and whether this approach can shorten hospital stays.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Prince of Wales Hospital

    Sydney, New South Wales, 2031, Australia

    Contact

  • Royal Prince Alfred Hospital

    Sydney, New South Wales, 2050, Australia

  • St Vincent's Hospital

    Sydney, New South Wales, 2010, Australia

    Contact

Conditions

Explore the condition pages connected to this study.