New radiation technique aims to spare rectal cancer patients from surgery
NCT ID NCT07337876
First seen Jan 15, 2026 · Last updated Jun 23, 2026 · Updated 24 times
Summary
This study tests whether a special MRI-guided radiation machine (MR-linac) can deliver high-dose radiation precisely to rectal tumors, allowing patients to avoid surgical removal of the rectum. About 100 people with early-stage rectal cancer will receive this radiation along with standard chemotherapy. The main goal is to see if patients can live without needing rectal surgery for at least two years.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospital Tübingen
RECRUITINGTübingen, Baden-Wurttemberg, 72074, Germany
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dose escalated radiotherapy with MRI guidance (MR-linac) plus standard chemotherapy
What this could lead to
If successful, this approach could allow many rectal cancer patients to keep their rectum and avoid major surgery, improving quality of life.
What could go wrong
This is a phase 2 trial with only 100 participants, so results may not apply to everyone. The treatment may not control the cancer as well as surgery, and there are risks from radiation and chemotherapy.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.