Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New pill could help PAD patients walk longer without pain

NCT ID NCT07223593

Symptom relief Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 09, 2026 · Updated 8 times

Summary

This study tests a once-daily pill called orforglipron in about 1205 people with peripheral artery disease (PAD) who have leg pain when walking. The goal is to see if the drug helps them walk farther without pain and improves their quality of life. Participants will be followed for about 58 weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 1,205 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have symptomatic PAD with intermittent claudication of Fontaine Stage II * Have an Ankle Brachial Index (ABI) of 0.9 or less Exclusion Criteria: * Have a body mass index (BMI) less than 23 kilogram per square meter (kg/m2) * Have Hemoglobin A1c (HbA1c) greater than 10% * Have walking ability limited by conditions other than PAD * Have a planned lower limb surgery or any other surgery affecting walking ability * Had peripheral revascularization procedure within 90 days prior to the day of screening or planning to undergo peripheral revascularization during the clinical trial * Had stroke, transient ischemic attack, myocardial infarction, coronary or carotid revascularization, or hospitalization for unstable angina pectoris within 60 days prior to screening * Have heart failure presently classified as being in New York Heart Association class III - IV

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Peripheral arterial disease are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Peripheral arterial disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    161 sites in 17 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • ASHA Clinical Research - Munster, LLC

    RECRUITING

    Hammond, Indiana, 46324, United States

  • Albert Schweitzer Ziekenhuis, locatie Dordwijk

    NOT_YET_RECRUITING

    Dordrecht, 3318 AT, Netherlands

  • All India Institute of Medical Sciences (AIIMS) - Nagpur

    RECRUITING

    Nagpur, 441108, India

  • All India Institute of Medical Sciences - Rishikesh

    RECRUITING

    Rishikesh, 249203, India

  • Alpha Recherche Clinique - Lévis

    RECRUITING

    Lévis, G6V 0C9, Canada

  • Alpine Research Organization

    RECRUITING

    Clinton, Utah, 84015, United States

  • Angel City Research Inc.

    NOT_YET_RECRUITING

    Los Angeles, California, 90010, United States

  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division

    RECRUITING

    Troy, Michigan, 48098, United States

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Barwon Health

    NOT_YET_RECRUITING

    Geelong, 3220, Australia

  • Beijing Pinggu District Hospital

    RECRUITING

    Beijing, 101200, China

  • Biopharma Informatic, LLC

    RECRUITING

    Houston, Texas, 77084, United States

  • Box Hill Hospital

    RECRUITING

    Box Hill, 3128, Australia

  • CEMEDIC

    RECRUITING

    Buenos Aires, C1407GTN, Argentina

  • CHRU Troussau

    RECRUITING

    Chambray-lès-Tours, 37170, France

  • CIPREC

    NOT_YET_RECRUITING

    Buenos Aires, 1061, Argentina

  • CIPREC

    RECRUITING

    Buenos Aires, C1119ACN, Argentina

  • Canberra Hospital

    RECRUITING

    Canberra, 2605, Australia

  • Capital Area Research, LLC

    RECRUITING

    Camp Hill, Pennsylvania, 17011, United States

  • Capitol Cardiology Associates - Lanham Office

    NOT_YET_RECRUITING

    Lanham, Maryland, 20706, United States

  • Cardio 1 Medical Clinic

    RECRUITING

    Winnipeg, R3L 1Z5, Canada

  • Cardiovascular Research of Northwest Indiana

    NOT_YET_RECRUITING

    Munster, Indiana, 46321, United States

  • Carient Heart & Vascular - Manassas

    NOT_YET_RECRUITING

    Manassas, Virginia, 20109, United States

  • Catharina Ziekenhuis

    NOT_YET_RECRUITING

    Eindhoven, 5623 EJ, Netherlands

  • Central India Cardiology and Research Institute

    NOT_YET_RECRUITING

    Nagpur, 440015, India

  • Centre Hospitalier Universitaire d'Angers

    RECRUITING

    Angers, 49933, France

  • Centre Hospitalier Universitaire de Nice - Hopital Pasteur

    RECRUITING

    Nice, 06000, France

  • Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou

    RECRUITING

    Rennes, 35033, France

  • Centro Avançado De Pesquisa, Estudos E Diagnóstico (CAPED) - Centro Médico RibeirãoShopping

    RECRUITING

    Ribeirão Preto, 14026-020, Brazil

  • Centro de Investigaciones Clínicas Baigorria

    NOT_YET_RECRUITING

    Granadero Baigorria, 2152, Argentina

  • Centro de Pesquisa Clinica do Coracao

    RECRUITING

    Aracaju, 49055-530, Brazil

  • Centro de Pesquisa Sao Lucas

    RECRUITING

    Campinas, 13060-803, Brazil

  • Centro de Salud e Investigaciones Médicas

    RECRUITING

    Santa Rosa, L6300, Argentina

  • Centrum Badań Klinicznych Piotr Napora lekarze sp.p.

    NOT_YET_RECRUITING

    Wroclaw, 51-162, Poland

  • Centrum Medyczne INTERCOR Sp. z o.o.

    RECRUITING

    Bydgoszcz, 85-605, Poland

  • Centrum Medyczne Komorniki

    RECRUITING

    Komorniki, 62-052, Poland

  • Chang Gung Medical Foundation-Linkou Branch

    RECRUITING

    Taoyuan, 333, Taiwan

  • Chang Gung Memorial Hospital at Kaohsiung

    RECRUITING

    Kaohsiung Niao Sung Dist, 83301, Taiwan

  • Clinical Research Partners, LLC

    RECRUITING

    Richmond, Virginia, 23226, United States

  • Corcare

    RECRUITING

    Toronto, M1B 5N1, Canada

  • Core Research Group

    RECRUITING

    Brisbane, 4064, Australia

  • DIM Clínica Privada

    RECRUITING

    Ramos Mejía, B1704ETD, Argentina

  • Daegu Catholic University Medical Center

    RECRUITING

    Daegu, 42472, South Korea

  • Deaconess Clinic- Gateway

    RECRUITING

    Newburgh, Indiana, 47630, United States

  • Del Sol Research Management, LLC

    RECRUITING

    Tucson, Arizona, 85715, United States

  • Derriford Hospital

    RECRUITING

    Plymouth, Pl6 8DH, United Kingdom

  • ERA Health Research - CardioNow - Lynnwood

    RECRUITING

    Lynnwood, Washington, 98036, United States

  • East Coast Institute for Research - Jefferson City

    RECRUITING

    Jefferson City, Tennessee, 37760, United States

  • Eastside Research Associates

    RECRUITING

    Redmond, Washington, 98052, United States

  • Emvera Health at Peak Heart & Vascular Surprise

    NOT_YET_RECRUITING

    Surprise, Arizona, 85378, United States

  • Floridian Clinical Research, LLC

    RECRUITING

    Miami Lakes, Florida, 33016-1518, United States

  • Flourish Research - Bowie

    RECRUITING

    Bowie, Maryland, 20715, United States

  • Fukuyama City Hospital

    RECRUITING

    Fukuyama, 721-8511, Japan

  • Fundacion Estudios Clinicos

    NOT_YET_RECRUITING

    Rosario, 2000, Argentina

  • Gershon Pain Specialists

    RECRUITING

    Virginia Beach, Virginia, 23454, United States

  • Go Centro Medico San Nicolás

    RECRUITING

    San Nicolás, 2900, Argentina

  • Gold Coast University Hospital

    RECRUITING

    Southport, 4215, Australia

  • Government Medical College - Kozhikode

    RECRUITING

    Kozhikode, 673008, India

  • Groupe hospitalier Paris saint Joseph

    RECRUITING

    Paris, 75014, France

  • Guangdong Provincial People's Hospital

    RECRUITING

    Guangzhou, 510000, China

  • Guardian Research Organization, LLC

    NOT_YET_RECRUITING

    Winter Park, Florida, 32792, United States

  • Hadassah Medical Center

    NOT_YET_RECRUITING

    Jerusalem, 9112001, Israel

  • Hakodate Municipal Hospital

    RECRUITING

    Hakodate, 041-8680, Japan

  • Heart of Australia

    NOT_YET_RECRUITING

    Brisbane, 4068, Australia

  • Heilongjiang Provincial Hospital

    RECRUITING

    Harbin, 150036, China

  • Hospital Universitário João de Barros Barreto

    NOT_YET_RECRUITING

    Belém, 66073-000, Brazil

  • Hospital de Clinicas de Porto Alegre

    RECRUITING

    Porto Alegre, 90035-903, Brazil

  • Hôpital Européen Georges Pompidou

    RECRUITING

    Paris, 75015, France

  • Hôpital Saint Philibert

    RECRUITING

    Lomme, 59160, France

  • INECO Neurociencias Oroño

    RECRUITING

    Rosario, 2000, Argentina

  • Imperial College Healthcare NHS Trust, Charing Cross Hospital

    RECRUITING

    London, W6 8RF, United Kingdom

  • Indiana University Health Methodist Hospital

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Inpatient Research Clinic

    RECRUITING

    Miami Lakes, Florida, 33014, United States

  • Instituto de Investigaciones Clinicas Rosario

    RECRUITING

    Rosario, S2000CVD, Argentina

  • Instituto de Investigaciones Clínicas Córdoba

    RECRUITING

    Córdoba, 5000, Argentina

  • Instituto de Molestias Cardiovasculares de Tatui

    RECRUITING

    Tatuí, 18270-170, Brazil

  • Instituto de Pesquisa clinica de Campinas

    RECRUITING

    Campinas, 13060-080, Brazil

  • Interventional Cardiology Medical Group

    RECRUITING

    West Hills, California, 91307, United States

  • InvivoCure

    RECRUITING

    Van Nuys, California, 91405, United States

  • Iwate Medical University Hospital

    RECRUITING

    Shiwa-gun Yahaba-cho, 028-3695, Japan

  • Japan Community Healthcare Organization Hokkaido Hospital

    RECRUITING

    Sapporo, 062-8618, Japan

  • Japanese Red Cross Musashino Hospital

    RECRUITING

    Musashino-shi, 180-8610, Japan

  • Jawaharlal Nehru Medical College

    RECRUITING

    Aligarh, 202002, India

  • Jiangsu Province Hospital

    RECRUITING

    Nanjing, 210029, China

  • KMH Cardiology Centres - Stoney Creek

    RECRUITING

    Stoney Creek, L8J 3W2, Canada

  • KO-MED Centra Kliniczne

    NOT_YET_RECRUITING

    Puławy, 24-100, Poland

  • Kansai Electric Power Hospital

    RECRUITING

    Osaka, 553-0003, Japan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    RECRUITING

    Kaohsiung City, 807, Taiwan

  • Kobe City Medical Center General Hospital

    RECRUITING

    Kobe, 650-0047, Japan

  • Kokura Memorial Hospital

    RECRUITING

    Kitakyushu, 802-8555, Japan

  • Korea University Anam Hospital

    RECRUITING

    Seoul, 02841, South Korea

  • Koujunkai Daido Clinic

    RECRUITING

    Nagoya, 457-8511, Japan

  • Lakeview Institute of Clinical Research

    RECRUITING

    Leesburg, Florida, 34748, United States

  • Lata Mangeshkar Hospital - Digdoh

    RECRUITING

    Nagpur, 440019, India

  • M. P. Birla Group - Belle Vue Clinic

    RECRUITING

    Kolkata, 700017, India

  • MEDIVASA

    RECRUITING

    Žilina, 01001, Slovakia

  • MICA - Medicina e Investigación Cardiometabólica

    NOT_YET_RECRUITING

    Del Viso, 1669, Argentina

  • Medical Corporation Sapporo Heart Center Sapporo Cardio Vascular Clinic

    RECRUITING

    Higashi, 007-0849, Japan

  • Mercy Gilbert Medical Center

    RECRUITING

    Gilbert, Arizona, 85297, United States

  • Mito Medical Center

    NOT_YET_RECRUITING

    Higashiibaraki, 311-3117, Japan

  • Moorgreen Hospital

    RECRUITING

    West End, SO30 3JB, United Kingdom

  • Municipal Toyonaka Hospital

    RECRUITING

    Toyonaka, 560-0055, Japan

  • NZOZ Twoje Zdrowie EL Sp. z o. o.

    RECRUITING

    Elblag, 82-300, Poland

  • Nakakinen clinic

    RECRUITING

    Naka, 311-0113, Japan

  • Nanjing First Hospital

    RECRUITING

    Nanjing, 210006, China

  • Nanjing First Hospital

    RECRUITING

    Nanjing, 210012, China

  • National Hospital Organization Kanazawa Medical Center

    RECRUITING

    Kanazawa, 920-8650, Japan

  • National Hospital Organization Osaka National Hospital

    RECRUITING

    Osaka, 540-0006, Japan

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 10002, Taiwan

  • NextStage Clinical Research - Waco

    RECRUITING

    Waco, Texas, 76712, United States

  • Nirmal Hospital Pvt Ltd.

    NOT_YET_RECRUITING

    Surat, 395002, India

  • Oita Oka Hospital

    NOT_YET_RECRUITING

    Ōita, 870-0192, Japan

  • Omi Medical Center

    RECRUITING

    Kusatsu, 525-0066, Japan

  • Osaka General Medical Center

    RECRUITING

    Osaka, 558-8558, Japan

  • Osaka Keisatsu Hospital

    RECRUITING

    Osaka, 543-0042, Japan

  • Peking University Third Hospital

    RECRUITING

    Beijing, 100091, China

  • Poliklinika Kardiologiczna Serce

    RECRUITING

    Leszno, 64-100, Poland

  • Pracownia Badań Klinicznych Salus

    NOT_YET_RECRUITING

    Wroclaw, 53-034, Poland

  • Priyanka Hospital & Cardiac Center

    NOT_YET_RECRUITING

    Jaipur, 302020, India

  • Przychodnie Grudziądz

    RECRUITING

    Grudziądz, 86-300, Poland

  • Radboudumc

    NOT_YET_RECRUITING

    Nijmegen, 6525 GA, Netherlands

  • Research Physicians Network, LLC

    RECRUITING

    Houston, Texas, 77089, United States

  • Research and Cardiovascular Corp.

    RECRUITING

    Ponce, 00717, Puerto Rico

  • Rocky Mountain Regional VA Medical Center

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

  • Royal North Shore Hospital

    NOT_YET_RECRUITING

    St Leonards, 2065, Australia

  • Royal Perth Hospital

    RECRUITING

    Perth, 6000, Australia

  • Royal Stoke University Hospital

    RECRUITING

    Stoke-on-Trent, ST4 6QG, United Kingdom

  • Saitama City Hospital

    RECRUITING

    Saitama, 336-8522, Japan

  • Sanatorio Finochietto

    RECRUITING

    Buenos Aires, C1187AAN, Argentina

  • Seikeikai Medical Corporation New Tokyo Heart Clinic

    RECRUITING

    Matsudo, 271-0077, Japan

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, 200023, China

  • Sherman Clinical Research

    RECRUITING

    Sherman, Texas, 75090, United States

  • Shinyurigaoka General Hospital

    RECRUITING

    Kawasaki, 215-0026, Japan

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, 610072, China

  • Sir Ganga Ram Hospital

    RECRUITING

    New Delhi, 110060, India

  • St Johns Center for Clinical Research

    RECRUITING

    Saint Augustine, Florida, 32086, United States

  • St. Vincent's Birmingham Hospital

    RECRUITING

    Birmingham, Alabama, 35205, United States

  • Stroobants Cardiovascular Center

    RECRUITING

    Lynchburg, Virginia, 24501, United States

  • Swansea University

    RECRUITING

    Swansea, SA2 8PP, United Kingdom

  • THEO Medical Concorde

    RECRUITING

    Laval, H7G 2E6, Canada

  • The Cardiovascular Center

    RECRUITING

    Redding, California, 96001, United States

  • The First Affiliated Hospital of Henan University of Science &Technology

    RECRUITING

    Luoyang Shi, 471003, China

  • The First Affiliated Hospital of Wenzhou Medical University

    RECRUITING

    Wenzhou, 325000, China

  • The First Affiliated Hospital of Xi'an Medical University

    RECRUITING

    Xi'an, 710077, China

  • The Fourth Affiliated Hospital of Harbin Medical University

    NOT_YET_RECRUITING

    Harbin, 150001, China

  • The Jackson Clinic

    RECRUITING

    Jackson, Tennessee, 38305, United States

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, 300052, China

  • Tianjin People' s Hospital

    RECRUITING

    Tianjin, 300121, China

  • Toronto General Hospital

    NOT_YET_RECRUITING

    Toronto, M5G 2C4, Canada

  • Unity Health Toronto, St. Michael's Hospital

    NOT_YET_RECRUITING

    Toronto, M5B 1W8, Canada

  • Universidade Federal de Goias

    RECRUITING

    Goiânia, 74605-020, Brazil

  • University of Yamanashi Hospital

    RECRUITING

    Chūō, 409-3898, Japan

  • University of the Sunshine Coast (UniSC) Clinical Trials - Meadowbrook

    RECRUITING

    Meadowbrook, 4131, Australia

  • Valley Clinical Trials, LLC dba Flourish Research

    RECRUITING

    Northridge, California, 91325, United States

  • Vijan Hospital & Research Centre

    RECRUITING

    Nashik, 422005, India

  • Wuhan University Medical College - Hubei Zhongshan Hospital

    RECRUITING

    Wuhan, 430000, China

  • Xuanwu Hospital Capital Medical University

    RECRUITING

    Beijing, 100053, China

  • Yamagata University Hospital

    RECRUITING

    Yamagata, 990-9585, Japan

  • Yokohama City Minato Red Cross Hospital

    RECRUITING

    Yokohama, 231-0801, Japan

  • Zhongshan Hospital,Fudan University

    RECRUITING

    Shanghai, 200032, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.