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New hope for hard-to-treat lymphoma: targeted drug combo enters phase 2 trial

NCT ID NCT04989621

First seen Apr 24, 2026 · Last updated Apr 30, 2026 · Updated 2 times

Summary

This study is testing whether a combination of two drugs (orelabrutinib and rituximab) followed by long-term orelabrutinib can shrink tumors or slow disease in people whose follicular lymphoma has come back or stopped responding to prior treatment. About 32 adults will receive the treatment, and researchers will measure how many patients respond and how long the benefit lasts. Because patients continue maintenance therapy indefinitely, this is a disease-control approach, not a cure.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Guangdong General Hospital

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact

  • Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University,

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 51000, China

    Contact

  • Sun Yat-sen Universitiy Cancer Center, Sun Yat-Sen University,

    RECRUITING

    Guangzhou, Guangdong, 51000, China

    Contact

Conditions

Explore the condition pages connected to this study.