Engineered donor cells aim to make stem cell transplants safer for blood cancer patients
NCT ID NCT03802695
First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 27 times
Summary
This early-phase study tests a new type of donor cell graft called Orca-Q in 300 people with blood cancers like leukemia or myelodysplastic syndromes who need a stem cell transplant. The graft is engineered from a donor's blood cells to try to reduce complications like graft-versus-host disease and improve recovery of the patient's blood cell counts. The main goals are to check safety and see how well the new graft helps the body accept the transplant.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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City of Hope
RECRUITINGDuarte, California, 91010, United States
Contact
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Emory University
ACTIVE_NOT_RECRUITINGAtlanta, Georgia, 30322, United States
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Froedtert Memorial Lutheran Hospital
WITHDRAWNMilwaukee, Wisconsin, 53226, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact
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Ohio State University
ACTIVE_NOT_RECRUITINGColumbus, Ohio, 43210, United States
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Stanford Health Care
RECRUITINGStanford, California, 94305, United States
Contact
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The University of Kansas Hospital
WITHDRAWNKansas City, Kansas, 66160, United States
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UC Davis
RECRUITINGSacramento, California, 95817, United States
Contact
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University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77054, United States
Contact
Conditions
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