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Iron showdown: pills vs IV for anemia in late pregnancy

NCT ID NCT07485023

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to treat anemia in pregnant women diagnosed after 34 weeks: taking iron pills daily or getting iron through a vein (IV). The goal is to see which approach raises hemoglobin levels better by the time of delivery. About 128 women will take part, and the results could help guide treatment choices for late-pregnancy anemia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Iron (oral or intravenous)
What this could lead to
If it works, this could show that early IV iron is a better option for quickly raising hemoglobin in late pregnancy, potentially reducing the need for blood transfusions.
What could go wrong
This is a small, early-stage trial (128 participants) that has not yet started recruiting. Results may not apply to all pregnant women, and IV iron carries rare risks like allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 128 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Women aged 18 years or older. * Singleton pregnancy. * Gestational age ≥34+0 weeks at the time of anemia diagnosis. * Hemoglobin \<11 g/dL measured as part of routine antenatal care. * Ongoing antenatal follow-up at Policlinico Umberto I. * Ability to understand study procedures and provide written informed consent. Exclusion Criteria: * • Known anemia not primarily due to iron deficiency. * Known hemoglobinopathies. * Severe anemia requiring immediate blood transfusion. * Previous severe hypersensitivity reaction to IV iron formulations. * Chronic hematologic disease. * Acute infection or inflammatory condition at enrollment. * Severe hepatic or renal impairment. * Any condition judged by the investigator to make participation unsafe.

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As listed by the trial registrant

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How to take part

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