Gut check: oral vaccine study probes leaky gut in healthy volunteers
NCT ID NCT04083950
First seen Dec 22, 2025 · Last updated May 23, 2026 · Updated 21 times
Summary
This study looks at how an oral typhoid vaccine temporarily changes the gut's barrier, making it more 'leaky,' and how the immune system responds. Ten healthy adults will take the vaccine, and researchers will measure sugar levels in urine and immune cells in blood to track these changes. The goal is to better understand gut health and immune reactions, not to treat or cure any disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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USDA, ARS, Western Human Nutrition Research Center
Davis, California, 95616, United States
Conditions
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