ALS drug edaravone tested for Long-Term safety in 124 patients
NCT ID NCT04577404
First seen Sep 30, 2025 · Last updated May 20, 2026 · Updated 21 times
Summary
This study looked at the long-term safety of an oral form of edaravone in 124 people with ALS over 96 weeks. ALS is a progressive nerve disease that weakens muscles. The main goal was to see how safe and tolerable the drug is when taken for a long time, not to cure the disease. Participants had already completed a previous edaravone study.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aichi Medical University Hospital
Nagakute-shi, Aichi-ken, 480-1195, Japan
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Alleghany General Hospital
Pittsburgh, Pennsylvania, 15212, United States
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CHU-Nice - Hopital Pasteur 2
Nice, Cedex 1, 06001, France
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Centre Hospitalier Esquirol
Limoges, Marcland, 87025, France
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Centre Hospitalier Universitaire (CHU) de Bordeaux
Bordeaux, 33400, France
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Deutsche Klinik fuer Diagnostik
Wiesbaden, Hesse, 65191, Germany
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Emory University - School of Medicine
Atlanta, Georgia, 30317-2819, United States
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Fondazione Serena Onlus - Azienda Ospedaliera Niguarda Ca Granda - Centro Clinico Nemo (Neuro Muscular Omnicentre)
Milan, 20162, Italy
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Fukushima Medical University Hospital
Fukushima, Fukushima, 960-1295, Japan
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Heritage Medical Research Clinic - University Of Calgary
Calgary, Alberta, T2N 4Z6, Canada
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Hopital Pierre Wertheimer - Hopital Neurologique
Paris, 75013, France
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Johns Hopkins University
Baltimore, Maryland, 21209, United States
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Juntendo University Hospital
Bunkyo-ku, Tokyo, 113-8431, Japan
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Kagawa University Hospital
Kita-gun, Kagawa-ken, 761-0793, Japan
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Kansai Electric Power Hospital Recruiting
Fukushima-ku, Osaka-shi, Osaka, 553-0003, Japan
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Kitasato University Hospital
Sagamihara, Kanagawa, 252-0375, Japan
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Medizinische Hochschule Hannover
Hanover, Lower Saxony, 30625, Germany
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Montreal Neurological Institute and Hospital
Montreal, Quebec, H3A 2B4, Canada
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Murakami Karindoh Hospital
Fukuoka, Fukuoka, 819-8585, Japan
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National Hospital Organization Chibahigashi National Hospital
Chiba, Chiba, 260-8712, Japan
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National Hospital Organization Hokkaido Medical Center
Sapporo, Hokkaido, 063-0005, Japan
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National Hospital Organization Iou National Hospital
Kanazawa, Ishikawa-ken, 920-0192, Japan
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National Hospital Organization Kumamoto Saishun Medical Center
Koshi-shi, Kumamoto, 861-1196, Japan
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National Hospital Organization Shizuoka Institute of Epilepsy and Neurological Disorders
Shizuoka, Shizuoka, 420-8688, Japan
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National Hospital Organization Toneyama Medical Center
Toyonaka-shi, Osaka, 560-8552, Japan
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Neurology Associates, P.C - Lincoln
Lincoln, Nebraska, 68506, United States
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Neuromuscular Research Center
Phoenix, Arizona, 85028, United States
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Niigata University Medical And Dental Hospital
Niigata, Niigata, 951-8520, Japan
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Ospedale San Raffaele (HSR) (Istituto Scientifico Universitario San Raffaele)
Milan, Lombardy, 20132, Italy
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Penn State Hershey Children's Hospital
Hershey, Pennsylvania, 17025, United States
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Shiga University of Medical Science Hospital
Ōtsu, Shiga, 520-2192, Japan
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St. Joseph's Hospital and Medical Center (SJHMC) - Barrow Neurological Institute (BNI) - The Gregory W. Fulton ALS and Neuromuscular Disease Center
Phoenix, Arizona, 85013, United States
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Texas Neurology, PA
Dallas, Texas, 75214, United States
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Toho University Omori Medical Center
Ōta-ku, Tokyo, 143-8541, Japan
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Tohoku University Hospital
Sendai, Miyagi, 980-8574, Japan
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Tokyo Metropolitan Neurological Hospital
Fuchū, Tokyo, 183-0042, Japan
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UF Health Cancer Center
Gainesville, Florida, 32610-3633, United States
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Universita degli Studi di Torino - Centro Regionale Esperto Per La Sclerosi Laterale Amiotrofica (CRESLA)
Turin, Piedmont, 10126, Italy
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University of Alberta - Walter C Mackenzie Health Sciences Centre (WCM)
Edmonton, Alberta, T6G 2B7, Canada
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University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
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Wake Forest University Baptist Medical Center (WFUBMC) - The J. Paul Sticht Center on Aging and Rehabilitation
Winston-Salem, North Carolina, 27157, United States
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Woodland Research Northwest
Rogers, Arkansas, 72758, United States
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Yokohama City University Hospital
Yokohama, Kanagawa, 236-0004, Japan
Conditions
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