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Bacterial cocktail may stop infant wheeze after bronchiolitis

NCT ID NCT05064631

First seen Nov 20, 2025 · Last updated Jun 16, 2026 · Updated 32 times

Summary

This study tested whether giving infants an oral bacterial lysate (Broncho-Vaxom) after a severe bout of bronchiolitis could reduce their risk of developing wheezing. 173 infants who had been hospitalized for bronchiolitis received either the bacterial lysate or a placebo for up to 24 months. The goal was to see if the treatment could prevent wheeze episodes and potentially lower the risk of asthma later in childhood.

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Contacts and locations

Locations

  • King's College Hospital NHS Foundation Trust

    London, SE5 9RS, United Kingdom

  • Royal London Hospital

    London, E1 1FR, United Kingdom

  • University Hospital Southampton NHS Foundation Trust

    Southampton, SO16 6YD, United Kingdom

Conditions

The condition(s) this trial relates to.

bronchiolitis Respiratory Sounds respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.