New care model aims to slash deaths from staph blood infections

NCT ID NCT06338176

Disease control Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested a centralized care model for patients with serious staph bloodstream infections. Over 2,500 adults in Alberta hospitals received automated alerts and expert recommendations to ensure they got the right tests, antibiotics, and specialist care. The goal was to improve adherence to best practices and reduce deaths, hospital stays, and readmissions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: clinical care pathway (automated alerts and evidence-based recommendations)
What this could lead to: If successful, this model could become a standard way to manage staph bloodstream infections, reducing deaths and hospital stays.
What could go wrong: This is an implementation study, not a test of a new drug. Results may vary across hospitals and may not apply outside Alberta.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

2,542 people

The number who actually took part.

Started

May 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age greater than 18 years at the time of hospital admission * Confirmed S. aureus bacteremia by blood culture performed at a laboratory in Alberta, Canada * Admitted to a designated acute care site in Alberta, Canada Exclusion Criteria: * The treating team believes death is imminent or inevitable . * GCD are C-level within 48 hours of admission. * The patient is transferred in from an out-of-province acute care center with a pre-existing SAB diagnosis.

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Conditions

The condition(s) this trial relates to.

staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Staph aureus bacteremia

Contacts and locations

Locations

Arthur J.E. Child Comprehensive Cancer Centre

Calgary, Alberta, Canada
Athabasca Healthcare Centre

Athabasca, Alberta, Canada
Barrhead Healthcare Centre

Barrhead, Alberta, Canada
Bassano Health Centre

Bassano, Alberta, Canada
Beaverlodge Municipal Hospital

Beaverlodge, Alberta, Canada
Big Country Hospital

Oyen, Alberta, Canada
Bonnyville Healthcare Centre

Bonnyville, Alberta, Canada
Bow Island Health Centre

Bow Island, Alberta, Canada
Boyle Healthcare Centre

Boyle, Alberta, Canada
Brooks Health Centre

Brooks, Alberta, Canada
Canmore General Hospital

Canmore, Alberta, Canada
Cardston Health Centre

Cardston, Alberta, Canada
Central Peace Health Complex

Spirit River, Alberta, Canada
Chinook Regional Hospital

Lethbridge, Alberta, Canada
Claresholm General Hospital

Claresholm, Alberta, Canada
Coaldale Health Centre

Coaldale, Alberta, Canada
Cold Lake Healthcare Centre

Cold Lake, Alberta, Canada
Consort Hospital and Care Centre

Consort, Alberta, Canada
Coronation Hospital and Care Centre

Coronation, Alberta, Canada
Cross Cancer Institute

Edmonton, Alberta, Canada
Crowsnest Pass Health Centre

Crowsnest Pass, Alberta, Canada
Daysland Health Centre

Daysland, Alberta, Canada
Devon General Hospital

Devon, Alberta, Canada
Didsbury District Health Services

Didsbury, Alberta, Canada
Drayton Valley Hospital and Care Centre

Drayton Valley, Alberta, Canada
Drumheller Health Centre

Drumheller, Alberta, Canada
Edson Healthcare Centre

Edson, Alberta, Canada
Elk Point Healthcare Centre

Elk Point, Alberta, Canada
Fairview Health Complex

Fairview, Alberta, Canada
Foothills Medical Centre

Calgary, Alberta, Canada
Fort Saskatchewan Community Hospital

Ft Saskatchewan, Alberta, Canada
Fox Creek Healthcare Centre

Fox Creek, Alberta, Canada
George McDougall - Smoky Lake Healthcare Centre

Smoky Lake, Alberta, Canada
Glenrose Rehabilitation Hospital

Edmonton, Alberta, Canada
Grande Cache Community Health Complex

Grande Cache, Alberta, Canada
Grande Prairie Regional Hospital

Grande Prairie, Alberta, Canada
Grey Nuns Community Hospital

Edmonton, Alberta, Canada
Grimshaw / Berwyn and District Community Health Centre

Grimshaw, Alberta, Canada
Hanna Health Centre

Hanna, Alberta, Canada
Hardisty Health Centre

Hardisty, Alberta, Canada
High Prairie Health Complex

High Prairie, Alberta, Canada
High River General Hospital

High River, Alberta, Canada
Hinton Healthcare Centre

Hinton, Alberta, Canada
Innisfail Health Centre

Innisfail, Alberta, Canada
Killam Health Centre

Killam, Alberta, Canada
Lacombe Hospital

Lacombe, Alberta, Canada
Lamont Health Centre

Lamont, Alberta, Canada
Leduc Community Hospital

Leduc, Alberta, Canada
Lloydminster Hospital

Lloydminster, Alberta, Canada
Manning Community Health Centre

Manning, Alberta, Canada
Mayerthorpe Healthcare Centre

Mayerthorpe, Alberta, Canada
Medicine Hat Regional Hospital

Medicine Hat, Alberta, Canada
Mineral Springs Hospital

Banff, Alberta, Canada
Misericordia Community Hospital

Edmonton, Alberta, Canada
Myron Thompson Health Centre

Sundre, Alberta, Canada
Northern Lights Regional Health Centre

Fort McMurray, Alberta, Canada
Northwest Health Centre

High Level, Alberta, Canada
Oilfields General Hospital

Black Diamond, Alberta, Canada
Olds Hospital and Care Centre

Olds, Alberta, Canada
Our Lady of the Rosary Hospital

Castor, Alberta, Canada
Peace River Community Health Centre

Peace River, Alberta, Canada
Peter Lougheed Centre

Calgary, Alberta, Canada
Pincher Creek Health Centre

Pincher Creek, Alberta, Canada
Ponoka Hospital

Ponoka, Alberta, Canada
Provost Health Centre

Provost, Alberta, Canada
Raymond Health Centre

Raymond, Alberta, Canada
Red Deer Regional Hospital Centre

Red Deer, Alberta, Canada
Redwater Health Centre

Redwater, Alberta, Canada
Rimbey Hospital

Rimbey, Alberta, Canada
Rocky Mountain House Health Centre

Rocky Mountain House, Alberta, Canada
Rockyview General Hospital

Rockyview, Alberta, Canada
Royal Alexandra Hospital

Edmonton, Alberta, Canada
Sacred Heart Community Healt

McLennan, Alberta, Canada
Seton - Jasper Healthcare Centre

Jasper, Alberta, Canada
Slave Lake Healthcare Centre

Slave Lake, Alberta, Canada
South Health Campus

Calgary, Alberta, Canada
St. Joseph's General Hospital

Vegreville, Alberta, Canada
St. Mary's Hospital

Camrose, Alberta, Canada
St. Theresa General Hospital

Fort Vermilion, Alberta, Canada
St. Therese - St. Paul Healthcare Centre

St. Paul, Alberta, Canada
Stettler Hospital

Stettler, Alberta, Canada
Strathmore District Health Services

Strathmore, Alberta, Canada
Sturgeon Community Hospital

St. Albert, Alberta, Canada
Swan Hills Healthcare Centre

Swan Hills, Alberta, Canada
Taber Health Centre

Taber, Alberta, Canada
Three Hills Health Centre

Three Hills, Alberta, Canada
Tofield Health Centre

Tofield, Alberta, Canada
Tom Baker Cancer Centre

Calgary, Alberta, Canada
Two Hills Health Centre

Two Hills, Alberta, Canada
University of Alberta Hospital

Edmonton, Alberta, Canada
Valleyview Health Centre

Valleyview, Alberta, Canada
Vermilion Health Centre

Vermilion, Alberta, Canada
Viking Health Centre

Viking, Alberta, Canada
Vulcan Community Health Centre

Vulcan, Alberta, Canada
Wabasca/Desmarais Healthcare Centre

Wabasca, Alberta, Canada
Wainwright Health Centre

Wainwright, Alberta, Canada
Westlock Healthcare Centre

Westlock, Alberta, Canada
Westview Health Centre

Westview Village, Alberta, Canada
Wetaskiwin Hospital

Wetaskiwin, Alberta, Canada
Whitecourt Healthcare Centre

Whitecourt, Alberta, Canada
William J Cadzow - Lac La Biche Health Care Centre

Lac La Biche, Alberta, Canada