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Brain-Guided blood pressure during surgery may cut risks

NCT ID NCT05308290

Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested whether keeping blood pressure within a range that ensures good blood flow to the brain during surgery is feasible and safe compared to usual care. Researchers enrolled 27 older adults having hip, knee, or lung surgery. They measured how often blood pressure fell outside the brain's comfort zone and checked for complications like heart attack, stroke, and delirium.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this approach could reduce complications like delirium and stroke after surgery in older patients.
What could go wrong
This is a very small pilot study (27 participants) with no phase, so results may not apply broadly. The intervention is a blood pressure management strategy, not a drug, so benefits may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

27 people

The number who actually took part.

Started

Jan 2023

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * planned hip or knee surgery (either for fracture or elective) or lung surgery * age ≥60 * ambulatory at baseline * expected duration of surgery \> 90 minutes Exclusion Criteria: * Planned concurrent surgery * Allergy to adhesive tape * Short Blessed Test score \>20 * Clinical diagnosis of dementia * Opinion of either the anesthesiologist or surgeon that the patient is not appropriate.

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Conditions

The condition(s) this trial relates to.

delirium hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delirium Hip arthropathy Hip fractures Surgery

Contacts and locations

Locations

  • The Johns Hopkins University

    Baltimore, Maryland, 21287, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.