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Brain scans and blood tests could predict best depression meds

NCT ID NCT05017311

First seen Feb 28, 2026

Summary

This study aims to find out if a special algorithm can predict which antidepressant will work best for each person with major depression. Researchers will use brain scans, EEGs, and blood tests from 400 adults to see if they can match people to the right medication faster. The goal is to move away from trial-and-error prescribing and make treatment more effective from the start.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre for Addiction and Mental Health

    RECRUITING

    Toronto, Ontario, M6J1H4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • McMaster University

    RECRUITING

    Hamilton, Ontario, L8P3B6, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nova Scotia Health Authority

    RECRUITING

    Halifax, Nova Scotia, B3H 2E2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ontario Shores Centre for Mental Health Sciences

    RECRUITING

    Whitby, Ontario, L1N 0H7, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queen's University

    RECRUITING

    Kingston, Ontario, K7L4X3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Royal Ottawa Mental Health Centre

    RECRUITING

    Ottawa, Ontario, K1Z 7K4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5T2S8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of British Columbia

    RECRUITING

    Vancouver, British Columbia, V6T2A1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 2T9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Saskatchewan

    RECRUITING

    Saskatoon, Saskatchewan, S7N 0W8, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.