Brain scans and blood tests could predict best depression meds

NCT ID NCT05017311

Recruiting now Knowledge-focused Sponsor: Nova Scotia Health Authority Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find out if a special algorithm can predict which antidepressant will work best for each person with major depression. Researchers will use brain scans, EEGs, and blood tests from 400 adults to see if they can match people to the right medication faster. The goal is to move away from trial-and-error prescribing and make treatment more effective from the start.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

Centre for Addiction and Mental Health
RECRUITING

Toronto, Ontario, M6J1H4, Canada
McMaster University
RECRUITING

Hamilton, Ontario, L8P3B6, Canada
Nova Scotia Health Authority
RECRUITING

Halifax, Nova Scotia, B3H 2E2, Canada
Ontario Shores Centre for Mental Health Sciences
RECRUITING

Whitby, Ontario, L1N 0H7, Canada
Queen's University
RECRUITING

Kingston, Ontario, K7L4X3, Canada
The Royal Ottawa Mental Health Centre
RECRUITING

Ottawa, Ontario, K1Z 7K4, Canada
University Health Network
RECRUITING

Toronto, Ontario, M5T2S8, Canada
University of British Columbia
RECRUITING

Vancouver, British Columbia, V6T2A1, Canada
University of Calgary
RECRUITING

Calgary, Alberta, T2N 2T9, Canada
University of Saskatchewan
RECRUITING

Saskatoon, Saskatchewan, S7N 0W8, Canada

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