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Tailored combo therapy boosts leukemia fight in adults

NCT ID NCT02881086

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 24 times

Summary

This study tested a personalized, intensive treatment plan for adults aged 18-55 with newly diagnosed acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma. The approach used strong chemotherapy, targeted drugs like nelarabine for T-cell ALL, and risk-based stem cell transplants. Over 1,000 participants were enrolled to see if this tailored strategy improves event-free survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospital of Frankfurt (Main)

    Frankfurt am Main, 60590, Germany

Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia lymphoblastic lymphoma Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.