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Quick fix for Kids' cavities? study tests fastest SDF application time

NCT ID NCT04655430

First seen May 06, 2026 · Last updated Jun 19, 2026 · Updated 10 times

Summary

This study tested different application times (3 seconds to 2 minutes) of 38% silver diamine fluoride solution to see which works best for stopping cavities in preschool children. Over 600 healthy kids aged 3-5 with at least one cavity participated. Researchers checked if the cavity surface became hard (arrested) and looked at tooth color changes. The goal is to find the shortest effective time to make treatment easier for young children.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Local kindergartens

    Hong Kong, Hong Kong

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

silver diamine fluoride (38% SDF) solution

What this could lead to

If successful, this could identify the shortest effective application time for SDF, making cavity treatment faster and easier for young children.

What could go wrong

This is a completed Phase 2/3 trial, but the optimal time may still vary by child. SDF can stain teeth black, which may be a cosmetic concern.

Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.