Quick fix for Kids' cavities? study tests fastest SDF application time

NCT ID NCT04655430

Completed Disease control Sponsor: The University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested different application times (3 seconds to 2 minutes) of 38% silver diamine fluoride solution to see which works best for stopping cavities in preschool children. Over 600 healthy kids aged 3-5 with at least one cavity participated. Researchers checked if the cavity surface became hard (arrested) and looked at tooth color changes. The goal is to find the shortest effective time to make treatment easier for young children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: silver diamine fluoride (38% SDF) solution
What this could lead to: If successful, this could identify the shortest effective application time for SDF, making cavity treatment faster and easier for young children.
What could go wrong: This is a completed Phase 2/3 trial, but the optimal time may still vary by child. SDF can stain teeth black, which may be a cosmetic concern.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EARLY CHILDHOOD CARIES

Contacts and locations

Locations

Local kindergartens

Hong Kong, Hong Kong

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Other studies related to the condition(s) this trial covers.