20 years of data reveal safer allergy test doses
NCT ID NCT02839551
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 20 years of data from over 1,200 patients to find the safest and most effective doses for drug provocation tests (DPTs) for beta-lactam allergies. Researchers analyzed past positive tests to create a new, simpler testing protocol. They will now test this new approach in a larger group to see if it saves time and is safer for patients.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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1,252 people
The number who actually took part.
- Started
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May 2016
- Finished
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Nov 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients with positive Drug Provocation Test (DPT) to beta-lactams Exclusion Criteria: * contra-indications to DPT * refusal of participation * vulnerable patients according to French regulation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University hospital of Montpellier
Montpellier, France, 34295, France
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Other studies related to the condition(s) this trial covers.
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