New study aims to measure resilience in opioid users
NCT ID NCT06954402
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is developing a way to measure resilience in people with opioid use disorder. Researchers will have 125 adults complete tasks that test thinking, emotions, and sense of control, both with and without stress. The goal is to see if these tasks match how resilient people say they are.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better ways to measure and understand resilience in people with opioid use disorder, potentially informing future treatments.
- What could go wrong
- This is an early-stage observational study, not a treatment trial. The tasks may not fully capture real-world resilience, and results may not apply to everyone with opioid use disorder.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 125 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Apr 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Can provide informed consent and can comply with study procedures 2. Adults aged ≥18 years 3. Meet Diagnostic and Statistical Manual (DSM-5) criteria for current opioid use disorder or are currently receiving pharmacotherapy for the treatment of OUD (e.g. methadone or buprenorphine maintenance treatment \[remission\]) 4. Urine sample that tests positive for opioids 5. Test negative for pregnancy at screening (females only) Exclusion Criteria: 1. Being pregnant or breastfeeding 2. Significant mental health or physical disorder, or life circumstances, that is judged by the investigators to interfere with study participation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Johns Hopkins University Bayview Medical Campus
NOT_YET_RECRUITINGBaltimore, Maryland, 21224, United States
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Johns Hopkins University Bayview Medical Campus
RECRUITINGBaltimore, Maryland, 21224, United States
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Other studies related to the condition(s) this trial covers.
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- Can AI and peer support close the opioid treatment gap?