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Could a Peer-Guided online program lift veteran depression?

NCT ID NCT07781228

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 24, 2026 · Last updated Aug 25, 2026 · Updated 1 time

Summary

This trial tests whether an online therapy program, supported by peer sessions, can reduce depression symptoms in veterans receiving primary care through the VA. About 400 veterans with moderate depression will either get enhanced usual care or the peer-supported online program. The study measures changes in depression severity and behavioral activation to see if this approach improves access to mental health care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Supported online self-help with peer support sessions, based on computerized cognitive behavioral therapy (cCBT)
What this could lead to
If effective, this approach could expand access to psychotherapy for veterans with depression, offering a scalable alternative to in-person sessions.
What could go wrong
The trial is early-stage and relies on self-reported outcomes; results may not generalize beyond VA settings, and peer support may not match professional therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Aug 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Must be enrolled in the VHA and currently receiving primary care services at VA Los Angeles or San Diego * Have access to computer (mobile or desktop), internet, telephone, and email * Able to read English text on a computer screen * Score 10 or higher on the PHQ-9 Exclusion Criteria: * Have moderate-high suicide risk (e.g. suicide flag) or active suicidality * Have other serious mental illness (e.g. bipolar disorder, psychosis) * Have medical disorder that would prevent/ interfere with participation (e.g. dementia/cognitive impairment, terminal illness)

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • VA Greater Los Angeles Healthcare System

    West Los Angeles, California, 90073-1003, United States

  • VA San Diego Healthcare System

    San Diego, California, 92161, United States

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