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New eye injection aims to halt blindness from dry AMD in major trial

NCT ID NCT06659445

First seen Oct 31, 2025 · Last updated Jun 17, 2026 · Updated 32 times

Summary

This study tests an experimental drug called ONL1204, given as an eye injection, to see if it can slow the growth of blind spots in people with geographic atrophy, an advanced form of dry age-related macular degeneration. About 324 adults aged 55 and older will receive either the drug or a sham injection. The goal is to preserve vision and prevent further damage to the retina.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Associated Retina Consultants

    RECRUITING

    Gilbert, Arizona, 85297, United States

    Contact

  • Associated Retina Consultants

    RECRUITING

    Phoenix, Arizona, 85020, United States

    Contact

  • Associated Retinal Consultants, P.C.

    RECRUITING

    Royal Oak, Michigan, 48073, United States

    Contact

  • Bay Area Retina Associates

    RECRUITING

    Walnut Creek, California, 94598, United States

    Contact

  • Charleston Neuroscience Institute

    RECRUITING

    Mt. Pleasant, South Carolina, 29464, United States

    Contact

  • Clinique d'ophtalmologie des Laurentides

    RECRUITING

    Boisbriand, Quebec, J7H0E8, Canada

    Contact

  • Doheny Image Reading Center

    RECRUITING

    Pasadena, California, 91103, United States

    Contact

  • Erie Retina Research, LLC (Clinic)

    RECRUITING

    Erie, Pennsylvania, 16505, United States

    Contact

  • Florida Retina Institute

    RECRUITING

    Orlando, Florida, 32806, United States

    Contact

  • Long Island Vitreoretinal Consultants

    RECRUITING

    Westbury, New York, 11590, United States

    Contact

  • North Carolina Retina Associates, S.C.

    RECRUITING

    Wake Forest, North Carolina, 27587, United States

    Contact

  • Pacific Northwest Retina

    RECRUITING

    Bellevue, Washington, 98004, United States

    Contact

  • Pacific Northwest Retina, PLLC

    RECRUITING

    Silverdale, Washington, 98383, United States

    Contact

  • Palmetto Retina Center

    RECRUITING

    West Columbia, South Carolina, 29169, United States

    Contact

  • Retina Associates of South Texas, PA

    RECRUITING

    San Antonio, Texas, 78240, United States

    Contact

  • Retina Associates of Western NY

    RECRUITING

    Rochester, New York, 14620, United States

    Contact

  • Retina Associates, Ltd.

    RECRUITING

    Elmhurst, Illinois, 60126, United States

    Contact

  • Retina Consultants of Southern Colorado

    RECRUITING

    Colorado Springs, Colorado, 80909-1183, United States

    Contact

  • Retina Consultants of Texas

    RECRUITING

    Beaumont, Texas, 77707, United States

    Contact

  • Retina Consultants of Texas

    RECRUITING

    Bellaire, Texas, 77401, United States

    Contact

  • Retina Consultants of Texas

    RECRUITING

    Katy, Texas, 77494, United States

    Contact

  • Retina Consultants of Texas

    RECRUITING

    San Antonio, Texas, 78240, United States

    Contact

  • Retina Consultants of Texas

    RECRUITING

    The Woodlands, Texas, 77384, United States

    Contact

  • Retina Group of New England

    RECRUITING

    Waterford, Connecticut, 06385, United States

    Contact

  • Retina Partners Midwest, P.C.

    RECRUITING

    Carmel, Indiana, 46032, United States

    Contact

  • Retina Research Institute at New England Retina Consultants

    RECRUITING

    Springfield, Massachusetts, 01107, United States

    Contact

  • Sierra Eye Associates

    RECRUITING

    Reno, Nevada, 89502, United States

    Contact

  • The Retina Institute

    RECRUITING

    St Louis, Missouri, 63128, United States

    Contact

Conditions

The condition(s) this trial relates to.

age-related macular degeneration dry age related macular degeneration Geographic Atrophy macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.