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Heart-Lung machine on the scene could save cardiac arrest patients

NCT ID NCT04620070

First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 27 times

Summary

This study tested whether starting a portable heart-lung machine (ECPR) right at the scene of a cardiac arrest could help more people survive and avoid brain damage. It included 221 adults aged 18-50 with witnessed cardiac arrest. The goal was to see if on-scene ECPR improves survival and neurological outcomes compared to standard care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Amsterdam UMC

    Amsterdam, Netherlands

  • ErasmusMC

    Rotterdam, 3015GD, Netherlands

  • Radboud

    Nijmegen, Netherlands

  • UMCG

    Groningen, Netherlands

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Extracorporeal cardiopulmonary resuscitation (ECPR) - a portable heart-lung machine started at the scene

What this could lead to

If it works, this could mean more people survive cardiac arrest with less brain damage, and it might become a standard emergency treatment.

What could go wrong

This is a completed trial, but results may not apply to all patients. The procedure is complex and risky, and benefits may be small or limited to specific groups.

Conditions

The condition(s) this trial relates to.

cardiac arrest Out-of-Hospital Cardiac Arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.