Can Omega-3 and diet advice tame fatty liver disease?
NCT ID NCT06627114
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study investigates whether a nutrition education program and omega-3 supplements can help people with non-alcoholic fatty liver disease (NAFLD) lose weight, improve liver enzymes, and lower cholesterol. Participants are randomly assigned to receive nutrition guidance, omega-3 capsules, or standard care. The goal is to see if these simple interventions can reduce liver fat and improve overall health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- omega-3 fatty acids (DHA and EPA)
- What this could lead to
- If successful, this could offer a simple, low-cost way to manage non-alcoholic fatty liver disease through diet and supplements.
- What could go wrong
- This is a relatively small study, and results may not apply to everyone. Omega-3 supplements can cause mild side effects like fishy aftertaste or digestive issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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159 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Mar 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 74 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18-74 years' old. * Ability to use a mobile phone. * Ultrasound examination diagnosed Patients with grade 1 and 2 non-alcoholic fatty liver disease. Exclusion Criteria: * supplementary intakes of n-3 PUFA within the previous 6 months. * pregnancy or breastfeeding. * chronic liver disease of other causes (autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, hereditary haemochromatosis, Wilson's disease, a1-anti-trypsin deficiency, coeliac disease). * hormone therapy and use of drugs like amiodarone, methotrexate, and corticosteroid. * three months. * chronic disease such as cardiovascular, gastrointestinal, thyroid, renal, cancer or pancreatic that assessed by a specialist. * The use of drugs known to be associated with liver steatosis (Drugs known to be capable of inducing steatosis and steatohepatitis can be divided into three broad groups: those that cause steatosis and steatohepatitis independently (e.g., amiodarone, perhexiline maleate); drugs which can precipitate latent NASH (e.g., tamoxifen); drugs which induce sporadic events of steatosis/steatohepatitis (e.g., carbamazepine).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hawler Medical University
Erbil, Kurdistan Region, 44001, Iraq
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