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Heart strain during lung surgery: new study investigates One-Lung breathing risks

NCT ID NCT07302243

Knowledge-focused Sponsor: Universitas Jenderal Soedirman Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 39 adults having chest surgery with one-lung ventilation to see if it causes heart muscle injury. Researchers measured troponin levels before and 6-12 hours after surgery. The goal is to understand how this common breathing technique affects the heart, which could lead to safer anesthesia practices.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the results show a clear link, this could help anesthesiologists adjust techniques to reduce heart strain during lung surgery.
What could go wrong
This is a small, single-group study with only 39 participants, so findings may not apply to all patients. It only measured markers at one time point, so long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

39 people

The number who actually took part.

Started

Jul 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

* Patients who refuse to participate in the study * Patients undergoing thoracotomy surgery involving manipulation of the cardiovascular system * Patients with a history of heart disease and/or current cardiac treatment * Patients with severe hepatic or renal impairment * Patients with contraindications or allergies to the medications used in the study * Pregnant or Lactating women

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-60 years who requiring surgical thoracotomy with one lung ventilation * Classified as ASA Physical Status I - III * Provide Informed concent ( patient or legal representative) Exclusion Criteria: \-

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Conditions

The condition(s) this trial relates to.

myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

One lung ventillation (OLV) Thoracic anesthesia

Contacts and locations

Locations

  • RSUD Prof. Margono Soekarjo

    Purwokerto, Central Java, 53122, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.