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New drug combo aims to fight rare cancers that Won't go away

NCT ID NCT04668300

First seen Oct 31, 2025 · Last updated May 21, 2026 · Updated 35 times

Summary

This study tests whether two immunotherapy drugs, oleclumab and durvalumab, can shrink or slow the growth of certain sarcomas (angiosarcoma, liposarcoma, and osteosarcoma) that have come back, spread, or stopped responding to standard treatment. About 75 adults and some teens (age 12+) will receive the drug combination. The goal is to see if the drugs help the immune system attack the cancer and control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.