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New drug combo aims to keep aggressive prostate cancer in check

NCT ID NCT03263650

First seen Oct 31, 2025 · Last updated Jun 14, 2026 · Updated 33 times

Summary

This study tests whether the drug olaparib can help control aggressive variant prostate cancer when given after initial chemotherapy. About 96 men will receive cabazitaxel, carboplatin, and prednisone first, then either olaparib or observation. The goal is to see if olaparib extends the time before the cancer progresses.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

prostate cancer prostate cancer, hereditary, 7

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.