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New implant could block opioid effects for months

NCT ID NCT05382091

First seen Feb 24, 2026 · Last updated May 22, 2026 · Updated 10 times

Summary

This study tests the safety of a long-acting naltrexone implant (OLANI) in 250 adults with opioid use disorder who want to prevent relapse. The implant is placed under the skin in the belly and releases medicine slowly to block opioids for weeks. Participants will receive up to four implants over about a year, and researchers will monitor side effects and opioid overdose events.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

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