New implant could help people stay off opioids for months

NCT ID NCT05382091

First seen Feb 24, 2026 · Last updated May 07, 2026 · Updated 5 times

Summary

This study tests the safety of a long-acting naltrexone implant (OLANI) in 250 adults with opioid use disorder who want to prevent relapse. The implant releases medication over several months to block the effects of opioids, helping patients focus on recovery. Participants will receive up to four implants over about a year, and researchers will monitor side effects and opioid overdose events.

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