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Gene therapy trial targets vision loss in retinitis pigmentosa

NCT ID NCT06388200

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 25 times

Summary

This study tests a gene therapy called OCU400 for people with retinitis pigmentosa, an eye disease that causes vision loss. The treatment is injected under the retina to help slow or improve vision. The trial enrolled 140 people aged 3 and older and measures how well they can navigate a maze in dim light after one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advanced Research, LLC.

    Deerfield Beach, Florida, 33064, United States

  • Associated Retina Consultants

    Phoenix, Arizona, 85020, United States

  • Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine

    Miami, Florida, 33136, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Calgary Retina Consultants

    Calgary, Alberta, T2H OC8, Canada

  • Erie Retina Research LLC

    Erie, Pennsylvania, 16507, United States

  • Gundersen Health System

    La Crosse, Wisconsin, 54601, United States

  • Research Institute of the McGill University Health Centre

    Montreal, Quebec, H2W 1L4, Canada

  • Retina Consultants of Texas

    Bellaire, Texas, 77401, United States

  • Retina Foundation of the Southwest

    Dallas, Texas, 75231, United States

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5, Canada

  • The University of British Columbia

    Vancouver, British Columbia, V5Z 3N9, Canada

  • University of Alberta

    Edmonton, Alberta, T6G 3E1, Canada

  • University of Southern Califormia

    La Jolla, California, 92093, United States

  • University of Southern California, Roski Eye Insitute

    Los Angeles, California, 90033, United States

  • Valley Retina Institute

    McAllen, Texas, 78503, United States

  • Vanderbilt Eye Institute

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.