Please sign in to follow a disease.
New study tests if better imaging during stent surgery improves heart outcomes
NCT ID NCT05493904
First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time
Summary
This study looks at 320 people with complex coronary artery disease who need a stent. It compares using a special camera (OCT) versus standard X-ray (angiography) to guide the stent placement. The goal is to see which method leads to better blood flow after the procedure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
320 people
The number who actually took part.
- Started
-
Nov 2022
- Expected to finish
-
Dec 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients \>18 years old 2. Patients with stable or unstable angina and complex coronary lesions\* 3. Patients who were indicated revascularization * Diameter stenosis \>90% by angiography * Diameter stenosis with 50\~90% with pre-interventional FFR ≤0.80 4. Patients who underwent implantation of 2nd generation drug-eluting stent * Definitions of complex coronary lesions 1. True bifurcation lesion (Medina 1,1,1/1,0,1/0,1,1) with side branch ≥2.5mm size 2. Chronic total occlusion (≥3 months) as target lesion 3. PCI for unprotected left main (LM) disease (LM os, body, distal LM bifurcation including non-true bifurcation) 4. Long coronary lesions (implanted stent ≥38 mm in length) 5. Multi-vessel PCI (≥2 major epicardial coronary arteries treated at one PCI session) 6. Multiple stents needed (≥3 more stent per patient) 7. In-stent restenosis lesion as target lesion 8. Severely calcified lesion (encircling calcium in angiography) 9. Left anterior descending (LAD), left circumflex artery (LCX), and right coronary artery (RCA) ostial lesion Exclusion Criteria: 1. Target lesions not amenable for PCI by operators' decision 2. Cardiogenic shock (Killip class IV) at presentation 3. Less than TIMI 3 flow of target vessel after index procedure 4. Intolerance to Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Heparin, Everolimus, Zotarolimus, Biolimus, or Sirolimus 5. Known true anaphylaxis to contrast medium (not allergic reaction but anaphylactic shock) 6. Renal insufficiency such that an additional contrast medium would be harmful for patient 7. Recent ST-segment elevation myocardial infarction (STEMI) 8. Inability to receive adenosine or nicorandil injection 9. Pregnancy or breast feeding 10. Non-cardiac co-morbid conditions are present with life expectancy \<2 year or that may result in protocol non-compliance (per site investigator's medical judgment) 11. Unwillingness or inability to comply with the procedures described in this protocol
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Angina pectoris are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chonnam National University Hospital
Gwangju, 61469, South Korea
-
Chung-Ang University Gwangmyeong Hospital
Gwangmyeong, South Korea
-
Samsung Medical Center
Seoul, South Korea
-
Seoul National University Hospital
Seoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Heart bypass surgeons test which vein layout keeps grafts open
- A soft patch that watches your heart beat in real time
- Zapping the ear: a new way to stop Post-Surgery heart rhythm problems?
- Squeeze a ball, lower your blood pressure? heart trial puts handgrip exercise to the test
- New heart scan aims to spot hidden plaque before it strikes
- Can a kidney ultrasound scan warn of kidney damage after heart bypass surgery?