New scan method could prevent unnecessary stents after heart attacks
NCT ID NCT05781087
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at 90 people who recently had a heart attack and have other artery narrowings that may or may not be dangerous. Researchers will use two types of scans—optical coherence tomography (OCT) and magnetic resonance angiography (MRA)—to see if they can tell which narrowings will get worse and which will stay stable. The goal is to help doctors decide which narrowings truly need stents, avoiding unnecessary risks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors decide which artery narrowings need stents after a heart attack, reducing unnecessary procedures and preventing future attacks.
- What could go wrong
- This is an early observational study with only 90 participants, so results may not apply to everyone. The scans may not accurately predict which narrowings will cause problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
90 people
The number who actually took part.
- Started
-
Apr 2023
- Expected to finish
-
Sep 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients after presentation with ST elevation myocardial infarction.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Successful primary percutaneous coronary intervention (PCI) within the previous week with no major complications at the index procedure * Bystander disease in a non-culprit vessel planned for clinically indicated staged angiography +/- PCI * Able to provide written informed consent. Exclusion Criteria: * Cardiogenic shock requiring intubation, inotropes or a mechanical support device * Creatinine clearance \<30ml/min * Prior coronary artery bypass grafting * Life expectancy less than 3 years * Pregnancy. * Target lesion in the left main coronary artery * Severe calcification or tortuosity that would threaten safe placement of a pressure wire or OCT catheter * Chronic total occlusion of a major epicardial vessel.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Coronary artery disease are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
King's College Hospital
London, SE5 9RS, United Kingdom
-
Royal Bournemouth Hospital
Bournemouth, United Kingdom
-
St Thomas' Hospital
London, SE1 7EH, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can heart stent patients go home in 6 hours?
- Clot-Busting copycat put to the test in heart attack care
- Can AI read heart scans to predict the next heart attack?
- Can a new drug cool the hidden inflammation that fuels heart disease?
- New CT scanner aims to cut unnecessary heart procedures
- Heart bypass surgeons test which vein layout keeps grafts open