New study aims to take the guesswork out of Kids' pain treatment
NCT ID NCT03794362
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is working on a tool to objectively measure pain and how well pain treatments work, especially for children and teens who may have trouble describing their pain. Researchers will use pupil responses to see how pain relievers affect nerve sensitivity. The study involves 120 participants aged 7 to 21 who are already receiving pain treatment at a clinic.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2018
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who are receiving pharmacological or non-pharmacological analgesic interventions as part of their regularly occurring clinical treatment.
- Ages
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7 to 21 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. The subject is 7 to 21 years of age 2. The subject is receiving an analgesic intervention in the Children's National Medical Center Pain Clinic 3. The subject is willing and able to provide written informed assent/parental consent to the study participation. Exclusion Criteria: 1. Eye pathology precluding pupillometry 2. Patients who are actively using opioids (history of use acceptable). Rationale: opioids constrict the pupil, and therefore concomitant opioid use would bias our results. 3. Subjects who are or may be pregnant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Children's National Health System
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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