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Promising vasculitis drug trial halted early

NCT ID NCT05376319

First seen May 12, 2026 · Last updated May 21, 2026 · Updated 2 times

Summary

This study tested a new drug, obinutuzumab, against the standard drug rituximab for people with a rare autoimmune disease that inflames blood vessels (ANCA-associated vasculitis). The goal was to see if obinutuzumab could better stop disease activity and clear harmful antibodies. However, the trial was stopped early and only enrolled 6 participants, so results are very limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.