Scientists dig into Obesity's secrets with tissue samples
NCT ID NCT03538210
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study collected blood, stomach, liver, intestine, and fat tissue from 360 severely obese patients undergoing bariatric surgery. The goal was to better understand how obesity and surgery affect the body, especially the digestive system. Researchers hope this knowledge will lead to improved obesity treatments and alternatives to surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward new treatments for obesity that don't require surgery.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly help patients. The findings may not lead to new therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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360 people
The number who actually took part.
- Started
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Feb 2018
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
severe obese subjects operated for bariatric surgery or reoperated for complication
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * severe obese subject with BMI above35 kg/m2, age above 18 ans who accept to participate * candidate for bariatric surgery according to HAS criteria * who will undergo either sleeve gastrectomy or gastric bypass * or who undergoesa revisional surgery for a complication of bariatric surgery * or who undergoes arevisional sugery fir insufficient weight loss * covered by an health insurance Exclusion Criteria: * psychiatric disease or undertanding disorder * alchool abuse or other addiction * organ failure (including liver, heart or kidney) * chronic life-threatening illness * inflamatory disease or immunosuppressive treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Lousi Mourier (HUPNVS)
Colombes, Île-de-France Region, 92700, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can going home sooner after Weight-Loss surgery save money without sacrificing safety?