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Fat tissue inflammation linked to Post-Surgery brain fog in obese patients?

NCT ID NCT04907565

Knowledge-focused Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 115 obese patients undergoing hip or heart surgery to see if inflammation in their fat tissue is linked to confusion or memory problems after the operation. Researchers collected blood and fat tissue samples during surgery and tracked patients' thinking abilities afterward. The goal was to better understand why some obese patients experience post-operative cognitive dysfunction.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help explain why some obese patients experience confusion or memory problems after surgery, pointing toward ways to prevent it.
What could go wrong
This is an observational study, not a treatment trial. It only looks for a link between fat tissue inflammation and cognitive issues, so it won't directly lead to a new therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

115 people

The number who actually took part.

Started

Sep 2021

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

prospective, monocentric study conduct in Toulouse university hospital

Ages

60 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patient about to receive a hip arthroplasty under general anesthesia, elective cardiac surgery with cardiopulmonary bypass, * patient with a MMSE score \> or = 20(/30), * patient able to give informed consent Exclusion Criteria: * emergency surgery, or surgery in a septic context, * patient with a known dementia or altered MMSE score (under 20)

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Inflammation Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment Obesity Post-operative confusion

Contacts and locations

Locations

  • Purpan University Hospital

    Toulouse, 31059, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.