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New cell therapy trial hopes to halt progressive MS

NCT ID NCT07139743

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 22 times

Summary

This early-stage study tests a new treatment called obe-cel for people with progressive multiple sclerosis (MS) that has not responded to other therapies. The main goal is to see if obe-cel is safe and what side effects it may cause. Eighteen adults will receive a single infusion of obe-cel after a short course of chemotherapy and will be monitored for up to 24 months. The study also looks for early signs that the treatment might slow or stop MS progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, United Kingdom

    Contact

  • Hospital Universitari i Politecnic La Fe de Valencia

    RECRUITING

    Valencia, Spain

    Contact

  • Hospital Universitario Vall d'Hebron - PPDS

    ACTIVE_NOT_RECRUITING

    Barcelona, Spain

  • Royal Hallamshire Hospital

    RECRUITING

    Sheffield, United Kingdom

    Contact

  • Stanford University

    NOT_YET_RECRUITING

    Redwood City, California, 94063, United States

    Contact

  • The National Hospital for Neurology & Neurosurgery

    RECRUITING

    London, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Western General Hospital Edinburgh - PPDSE Edinburgh

    RECRUITING

    Edinburgh, United Kingdom

    Contact

Conditions

Explore the condition pages connected to this study.