Could common bladder medications change how men ejaculate? a study investigates
NCT ID NCT07736560
First seen Jul 30, 2026 · Last updated Aug 14, 2026 · Updated 3 times
Summary
This study looks at whether antimuscarinic drugs used for overactive bladder (OAB) affect how long ejaculation lasts and the time before a man can ejaculate again. Researchers will follow men aged 20 to 50 who are prescribed tolterodine or propiverine for OAB. Participants fill out questionnaires before treatment and again at one and two months. The goal is to see if these bladder medications have any unintended effects on sexual function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- antimuscarinic drugs (tolterodine or propiverine) used for overactive bladder
- What this could lead to
- If the study finds a link, it could help doctors choose OAB treatments that minimize sexual side effects in men.
- What could go wrong
- This is a small observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all men.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
40 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Jun 2026
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Male patients aged 20-50 presenting to our urology outpatient clinic with overactive bladder symptoms and initiated on antimuscarinic therapy or mirabegron as part of routine clinical care
- Ages
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20 to 50 years
- Sex
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Male participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male patients aged 20-50 years * Diagnosis of overactive bladder (OAB) confirmed clinically * Sexually active * Willing to complete questionnaires at all three time points Exclusion Criteria: * Previous use of antimuscarinic or beta-3 agonist medications * Neurological disorders affecting bladder or sexual function (e.g., multiple sclerosis, Parkinson's disease, spinal cord injury) * Prior pelvic surgery or radiotherapy * Use of medications known to affect ejaculatory function (e.g., alpha-blockers, SSRIs, antipsychotics) * Active urinary tract infection * Uncontrolled diabetes mellitus * Unwillingness to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Başakşehir Çam and Sakura City Hospital, Department of Urology
Istanbul, Istanbul, 34200, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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