Can a simple supplement boost recovery after a broken hip?
NCT ID NCT05971173
First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 3 times
Summary
This pilot study tested whether giving older adults (ages 65-89) nutritional supplements like Juven and Centrum Silver before and after hip fracture surgery could improve their recovery. The study enrolled 40 participants and tracked complications, hospital readmissions, and quality of life for 26 weeks. The goal was to see if this approach is worth testing in a larger trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Nutritional supplements (Juven and Centrum Silver 50+)
- What this could lead to
- If it works, this could point toward a simple, low-cost way to improve recovery and reduce complications after hip fracture surgery in older adults.
- What could go wrong
- This is a very early pilot study with only 40 participants, so results may not be generalizable. The supplements are over-the-counter and unlikely to cause harm, but the study is too small to prove effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
-
40 people
The number who actually took part.
- Started
-
Sep 2023
- Finished
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Jun 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
65 to 89 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Provision of signed and dated informed consent form 2. Male or female, aged 65-89 years 3. Closed fracture of the proximal femur including the anatomic areas of femoral neck, intertrochanteric and subtrochanteric region 4. Patient indicated for surgical treatment (surgical fixation or arthroplasty) as per orthopaedic surgeon 5. Ability to take oral medication and be willing to adhere to the study drug regimen and to the nutritional guidance provided by nutritional experts. Exclusion Criteria: 1. Patients with open fractures 2. Surgical treatment other than surgical fixation or arthroplasty, such as proximal femur resection 3. Known allergic reactions to components of the study drugs or who do not tolerate oral nutritional supplementation (e.g. total parenteral nutrition or food allergies) 4. Decisional impairment 5. Prisoners
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UT Health San Antonio Department of Orthopedics
San Antonio, Texas, 78229, United States
-
University Health System
San Antonio, Texas, 78229, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a gentler spinal anesthesia keep frail patients' blood pressure steadier during hip surgery?
- Can diet and exercise rebuild strength after a hip fracture?
- Can a Bone-Strengthening infusion given right after hip surgery prevent a second break?