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New nursing protocol aims to prevent deadly clots after heart surgery

NCT ID NCT07347652

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special nursing care protocol can prevent deep vein thrombosis (DVT) in patients recovering from on-pump cardiac surgery. The protocol includes using devices to improve blood flow, blood thinners, early patient movement, hydration, and education. Researchers will compare 67 patients who receive this protocol against those getting standard care, tracking clot rates over 3 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nursing care protocol (including IPC devices, anticoagulant therapy, early risk identification, ambulation, hydration, and patient education)
What this could lead to
If successful, this could establish a standard nursing protocol that significantly reduces dangerous blood clots after heart surgery, improving patient safety.
What could go wrong
This is a small, single-center study with only 67 participants, so results may not apply broadly. The protocol combines existing methods, so dramatic breakthroughs are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

67 people

The number who actually took part.

Started

Jun 2025

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:Inclusion Criteria Patients will be eligible for participation in the study if they meet all of the following criteria: 1. Adult patients aged 18 years or older. 2. Patients scheduled to undergo elective or urgent on-pump cardiac surgery using cardiopulmonary bypass (e.g., coronary artery bypass grafting, valve replacement or repair, or combined procedures). 3. Both male and female patients. 4. Patients admitted to the participating cardiac surgery unit during the study period. 5. Patients with no evidence of preoperative deep vein thrombosis (DVT) or pulmonary embolism (PE) as confirmed by clinical assessment and/or Doppler ultrasonography when indicated. 6. Patients who are hemodynamically stable postoperatively and eligible to receive mechanical and/or pharmacological thromboprophylaxis. 7. Patients able to understand the study procedures and provide written informed consent (or consent obtained from a legal representative when applicable). 8. Patients expected to survive for at least three months postoperatively, allowing completion of the follow-up period. Exclusion Criteria:Exclusion Criteria Patients will be excluded from the study if they meet any of the following criteria: 1. History of deep vein thrombosis (DVT) or pulmonary embolism (PE) within the previous six months. 2. Known congenital or acquired coagulation disorders, including but not limited to hemophilia, thrombophilia, or antiphospholipid syndrome. 3. Patients receiving long-term therapeutic anticoagulation (e.g., warfarin, direct oral anticoagulants) for other medical indications prior to surgery. 4. Contraindications to pharmacological thromboprophylaxis, such as: * Active bleeding * Severe thrombocytopenia (platelet count \<50,000/µL) * History of heparin-induced thrombocytopenia (HIT) 5. Contraindications to mechanical prophylaxis, including: * Severe peripheral arterial disease * Skin ulcers, infections, or recent lower-limb surgery preventing device application 6. Patients undergoing off-pump cardiac surgery or minimally invasive cardiac procedures not requiring cardiopulmonary bypass. 7. Emergency surgery requiring immediate intervention where preoperative assessment and consent cannot be obtained. 8. Pregnant or postpartum women. 9. Patients with severe renal or hepatic failure that may interfere with anticoagulant metabolism or increase bleeding risk. 10. Patients with documented malignancy under active treatment associated with a markedly elevated thrombotic risk. 11. Patients unwilling or unable to comply with the study protocol or follow-up schedule.

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Conditions

The condition(s) this trial relates to.

venous thromboembolism Venous Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Facility of Nursing

    Nicosia, Cyprus

More trials for these conditions

Other studies related to the condition(s) this trial covers.