New nursing protocol aims to prevent deadly clots after heart surgery
NCT ID NCT07347652
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a special nursing care protocol can prevent deep vein thrombosis (DVT) in patients recovering from on-pump cardiac surgery. The protocol includes using devices to improve blood flow, blood thinners, early patient movement, hydration, and education. Researchers will compare 67 patients who receive this protocol against those getting standard care, tracking clot rates over 3 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nursing care protocol (including IPC devices, anticoagulant therapy, early risk identification, ambulation, hydration, and patient education)
- What this could lead to
- If successful, this could establish a standard nursing protocol that significantly reduces dangerous blood clots after heart surgery, improving patient safety.
- What could go wrong
- This is a small, single-center study with only 67 participants, so results may not apply broadly. The protocol combines existing methods, so dramatic breakthroughs are unlikely.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
67 people
The number who actually took part.
- Started
-
Jun 2025
- Expected to finish
-
Mar 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria:Inclusion Criteria Patients will be eligible for participation in the study if they meet all of the following criteria: 1. Adult patients aged 18 years or older. 2. Patients scheduled to undergo elective or urgent on-pump cardiac surgery using cardiopulmonary bypass (e.g., coronary artery bypass grafting, valve replacement or repair, or combined procedures). 3. Both male and female patients. 4. Patients admitted to the participating cardiac surgery unit during the study period. 5. Patients with no evidence of preoperative deep vein thrombosis (DVT) or pulmonary embolism (PE) as confirmed by clinical assessment and/or Doppler ultrasonography when indicated. 6. Patients who are hemodynamically stable postoperatively and eligible to receive mechanical and/or pharmacological thromboprophylaxis. 7. Patients able to understand the study procedures and provide written informed consent (or consent obtained from a legal representative when applicable). 8. Patients expected to survive for at least three months postoperatively, allowing completion of the follow-up period. Exclusion Criteria:Exclusion Criteria Patients will be excluded from the study if they meet any of the following criteria: 1. History of deep vein thrombosis (DVT) or pulmonary embolism (PE) within the previous six months. 2. Known congenital or acquired coagulation disorders, including but not limited to hemophilia, thrombophilia, or antiphospholipid syndrome. 3. Patients receiving long-term therapeutic anticoagulation (e.g., warfarin, direct oral anticoagulants) for other medical indications prior to surgery. 4. Contraindications to pharmacological thromboprophylaxis, such as: * Active bleeding * Severe thrombocytopenia (platelet count \<50,000/µL) * History of heparin-induced thrombocytopenia (HIT) 5. Contraindications to mechanical prophylaxis, including: * Severe peripheral arterial disease * Skin ulcers, infections, or recent lower-limb surgery preventing device application 6. Patients undergoing off-pump cardiac surgery or minimally invasive cardiac procedures not requiring cardiopulmonary bypass. 7. Emergency surgery requiring immediate intervention where preoperative assessment and consent cannot be obtained. 8. Pregnant or postpartum women. 9. Patients with severe renal or hepatic failure that may interfere with anticoagulant metabolism or increase bleeding risk. 10. Patients with documented malignancy under active treatment associated with a markedly elevated thrombotic risk. 11. Patients unwilling or unable to comply with the study protocol or follow-up schedule.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cardiac on-pump surgery are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Facility of Nursing
Nicosia, Cyprus
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a risk score plus a blood test catch dangerous leg clots after heart surgery?
- Can a simple score predict dangerous blood clots after chest surgery?
- Can a stent heal leg ulcers that Won't close?
- Could a simple pill replace painful shots for new moms at risk of clots?
- Stick-On ultrasound patch could spot hidden clots and heart trouble in real time