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Nurse-led oxygen weaning cuts hospital time for babies with bronchiolitis?

NCT ID NCT06621641

Knowledge-focused Sponsor: Dr. Behcet Uz Children's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a nurse-led weaning protocol for high-flow nasal cannula (HFNC) oxygen therapy in 150 infants aged 1-24 months hospitalized with bronchiolitis. The goal was to see if a structured weaning plan could reduce the time on HFNC, shorten hospital stays, and lower costs. The study compared outcomes between infants managed with the protocol and those receiving usual care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

150 people

The number who actually took part.

Started

Oct 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

1 month to 24 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients older than 1 month and younger than 24 months of age; hospitalized at the PICU with the intention of treatment with HFNC at least for the upcoming 4 hours * Patients with moderate and severe RAS(Respiratory Assessment Scale) requiring HFNC * Written informed consent signed and dated by the patient or one relative in case that the patient is unable to consent, after full explanation of the study by the investigator and prior to study participation Exclusion Criteria: * İnfants born before 32 weeks of gestation or those with cardiopulmonary, genetic, congenital, or neuromuscular abnormalities. * Patient with an indication for immediate noninvasive ventilation (NIV) * Patients deemed at high risk for the need for non-invasive mechanical ventilation within the next 4 hours * Hemodynamic instability

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Conditions

The condition(s) this trial relates to.

bronchiolitis respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bronchiolitis High flow nasal cannula Respiratory failure (pediatric patients)

Contacts and locations

Locations

  • Acibadem University, Acibadem Altunizade Hospital

    Istanbul, Turkey (Türkiye)

  • Aydin Obstetric and pediatrics Hospital

    Aydin, 09020, Turkey (Türkiye)

  • Cam Sakura Research and Training Hospital

    Istanbul, 34001, Turkey (Türkiye)

  • Erzurum Regional Research and Training Hospital

    Erzurum, 25180, Turkey (Türkiye)

  • Istanbul Aydin University

    Istanbul, Turkey (Türkiye)

  • The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training Hospital

    Izmir, Turkey (Türkiye)

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