Blood test for clot risk? study checks monthly changes
NCT ID NCT01559207
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether levels of nucleosomes and free DNA in the blood change from month to month in healthy people and in those who have had a blood clot (venous thromboembolism). Researchers measured these markers monthly for six months in 15 healthy volunteers and 15 patients with a history of clots. The goal was to see if these markers are stable enough to be useful for monitoring clot risk.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
-
120 people
The number who actually took part.
- Start date
-
Apr 2013
- Finished
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Oct 2014
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population is composed of 15 healthy volunteers with no history of VTE (group "T") and 100 patients with VTE (group "P"). Fifteen randomly selected members of group P make up the sub-group "Px".
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The patient or volunteer must have given his/her informed and signed consent * The patient or volunteer must be insured or beneficiary of a health insurance plan * The patient or volunteer is available for 6 months of follow-up For group "P": * patient with a history of VTE For group "T": * healthy volunteer * no history of VTE * no history of chronic disease * no history of neoplastic disease * no history of chronic infection * not taking anticoagulants, antiplatelet medications * no acute disease or infection during the last 2 weeks Exclusion Criteria: * The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, under tutorship or curatorship * The patient refuses to sign the consent * It is impossible to correctly inform the patient * The patient is pregnant, parturient, or breastfeeding * The patient gave birth in the past three months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de Nîmes - Hôpital Universitaire Carémeau
Nîmes, 30029, France
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Other studies related to the condition(s) this trial covers.
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