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Scientists hunt for hidden sources of lung infections in cystic fibrosis

NCT ID NCT05686837

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 37 times

Summary

This study aims to understand how nontuberculous mycobacteria (NTM) spread among people with cystic fibrosis (CF). NTM infections are hard to treat and common in CF, but their sources are unclear. Researchers will track 100 participants with CF and NTM, testing dust and water in clinics and mapping home water sources. The goal is to find where infections come from and how to prevent them.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dell Children's Ascension

    Austin, Texas, 78723, United States

  • Johns Hopkins Cystic Fibrosis Center

    Baltimore, Maryland, 21287, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • The University of Vermont Medical Center

    Colchester, Vermont, 05446, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75309, United States

  • UVA Health University Medical Center

    Charlottesville, Virginia, 22908, United States

  • UW Medical Center

    Seattle, Washington, 98195, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help identify how NTM infections spread in healthcare settings and homes, leading to better prevention strategies for people with cystic fibrosis.

What could go wrong

This is an observational study, not a treatment trial. It may not find clear transmission links, and results may not apply to all settings or patients.

Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.